Who owns IONIS PHARMACEUTICALS INC?
Prices and market caps: Cboe delayed data, at least 15 minutes delayed. Not real-time. Fundamentals from company filings.
Institutional ownership of IONS from SEC Form 13F filings across 514 reporting managers. All positions are from one synchronized reporting period — 2026-06-30 books, filed up to 45 days after quarter end — so every row is comparable.
As of the 2026-06-30 reporting period, 514 institutions disclosed 179.7M shares of IONIS PHARMACEUTICALS INC worth $14.26B — about 108.6% of shares outstanding; the largest disclosed holder is FMR LLC. Source: SEC Form 13F filings, parsed by EvidInvest.
514
13F holders
$14.26B
value, 2026 filers
108.6%
of shares outstanding (179.7M sh)
73
new positions (2026 filers)
Top institutional holders
ordered by shares owned · positions as of 2026-06-30 · % of fund = share of the manager's own book · % of co. = share of IONS's shares outstanding
| # | Manager | Shares | Value | % of fund | % of co. | Δ shares QoQ |
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 24.6M | $1.95B | 0.1% | 14.9% | +0.3% |
| 2 | Capital World Investors | 21.7M | $1.72B | 0.2% | 13.1% | +2.3% |
| 3 | BlackRock, Inc. | 10.7M | $848.8M | 0.0% | 6.5% | +2.5% |
| 4 | VANGUARD PORTFOLIO MANAGEMENT LLC | 7.9M | $623.2M | 0.0% | 4.8% | +0.6% |
| 5 | WELLINGTON MANAGEMENT GROUP LLP | 7.7M | $606.7M | 0.1% | 4.6% | +19.7% |
| 6 | VANGUARD CAPITAL MANAGEMENT LLC | 7.2M | $571.8M | 0.0% | 4.4% | +1.3% |
| 7 | TWO SIGMA INVESTMENTS, LP | 6.3M | $495.7M | 0.4% | 3.8% | +6.7% |
| 8 | ROYAL BANK OF CANADA | 6.2M | $490.2M | 0.1% | 3.7% | +62.6% |
| 9 | STATE STREET CORP | 4.3M | $343.7M | 0.0% | 2.6% | +8.5% |
| 10 | T. Rowe Price Investment Management, Inc. | 4.0M | $313.9M | 0.2% | 2.4% | -35.7% |
| 11 | GEODE CAPITAL MANAGEMENT, LLC | 3.6M | $294.8M | 0.0% | 2.2% | -10.0% |
| 12 | PRICE T ROWE ASSOCIATES INC /MD/ | 3.2M | $252.5M | 0.0% | 1.9% | +5.3% |
| 13 | JPMORGAN CHASE & CO | 2.7M | $216.2M | 0.0% | 1.6% | +13.0% |
| 14 | Artisan Partners Limited Partnership | 2.6M | $209.3M | 0.3% | 1.6% | +28.3% |
| 15 | Tweedy, Browne Co LLC | 2.3M | $180.8M | 13.7% | 1.4% | +0.2% |
| 16 | Deep Track Capital, LP | 2.2M | $174.4M | 2.5% | 1.3% | +12.8% |
| 17 | GOLDMAN SACHS GROUP INC | 2.1M | $167.3M | 0.0% | 1.3% | +24.1% |
| 18 | BAKER BROS. ADVISORS LP | 2.0M | $162.4M | 0.8% | 1.2% | 0.0% |
| 19 | DEERFIELD MANAGEMENT COMPANY, L.P. | 2.0M | $157.0M | 1.6% | 1.2% | 0.0% |
| 20 | AMERICAN CENTURY COMPANIES INC | 1.9M | $154.4M | 0.1% | 1.2% | +17.0% |
| 21 | FRANKLIN RESOURCES INC | 1.6M | $128.7M | 0.0% | 1% | +3.1% |
| 22 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1.6M | $127.3M | 0.0% | 1% | +1.4% |
| 23 | BARCLAYS PLC | 1.6M | $127.1M | 0.0% | 1% | +453.0% |
| 24 | Pictet Asset Management Holding SA | 1.6M | $127.0M | 0.1% | 1% | +11.3% |
| 25 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 1.5M | $115.3M | 0.0% | 0.9% | -1.4% |
Source: SEC Form 13F-HR filings (institutional managers over $100M in US-listed positions). 13Fs disclose long positions only, up to 45 days after quarter end; each manager's latest filed quarter is shown per row and dollar values are the manager's filed marks. Aggregates labeled "2026 filers" count only managers whose latest book is a 2026 quarter. Related: valuation · options positioning · supply chain. Research, not investment advice.