Who owns LEXICON PHARMACEUTICALS, INC.?
Prices and market caps: Cboe delayed data, at least 15 minutes delayed. Not real-time. Fundamentals from company filings.
Institutional ownership of LXRX from SEC Form 13F filings across 149 reporting managers. All positions are from one synchronized reporting period — 2026-06-30 books, filed up to 45 days after quarter end — so every row is comparable.
As of the 2026-06-30 reporting period, 149 institutions disclosed 364.6M shares of LEXICON PHARMACEUTICALS, INC. worth $875.1M — about 83.3% of shares outstanding; the largest disclosed holder is Artal Group S.A.. Source: SEC Form 13F filings, parsed by EvidInvest.
149
13F holders
$875.1M
value, 2026 filers
83.3%
of shares outstanding (364.6M sh)
44
new positions (2026 filers)
Top institutional holders
ordered by shares owned · positions as of 2026-06-30 · % of fund = share of the manager's own book · % of co. = share of LXRX's shares outstanding
| # | Manager | Shares | Value | % of fund | % of co. | Δ shares QoQ |
|---|---|---|---|---|---|---|
| 1 | Artal Group S.A. | 175.2M | $420.4M | 45.1% | 40% | +13.2% |
| 2 | FMR LLC | 51.8M | $124.3M | 0.0% | 11.8% | +14.9% |
| 3 | Siren, L.L.C. | 44.3M | $106.3M | 2.2% | 10.1% | 0.0% |
| 4 | Sessa Capital IM, L.P. | 19.0M | $45.5M | 0.8% | 4.3% | +5.8% |
| 5 | BlackRock, Inc. | 17.3M | $41.6M | 0.0% | 4% | +422.2% |
| 6 | VANGUARD CAPITAL MANAGEMENT LLC | 9.9M | $23.8M | 0.0% | 2.3% | +4.0% |
| 7 | Point72 Asset Management, L.P. | 8.3M | $19.8M | 0.0% | 1.9% | +5.6% |
| 8 | GEODE CAPITAL MANAGEMENT, LLC | 6.2M | $15.0M | 0.0% | 1.4% | +97.0% |
| 9 | STATE STREET CORP | 4.9M | $11.8M | 0.0% | 1.1% | +410.1% |
| 10 | VANGUARD PORTFOLIO MANAGEMENT LLC | 2.4M | $5.7M | 0.0% | 0.5% | +331.3% |
| 11 | NORTHERN TRUST CORP | 2.0M | $4.7M | 0.0% | 0.4% | +298.0% |
| 12 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 2.0M | $4.7M | 0.0% | 0.4% | +49.2% |
| 13 | VANGUARD FIDUCIARY TRUST CO | 1.6M | $3.9M | 0.0% | 0.4% | +22.7% |
| 14 | CITADEL ADVISORS LLC | 1.6M | $3.8M | 0.0% | 0.4% | +46.2% |
| 15 | Ishara Investments LP | 1.3M | $3.1M | 2.2% | 0.3% | +40.9% |
| 16 | MILLENNIUM MANAGEMENT LLC | 1.1M | $2.7M | 0.0% | 0.3% | -77.1% |
| 17 | RENAISSANCE TECHNOLOGIES LLC | 1.1M | $2.7M | 0.0% | 0.3% | -29.6% |
| 18 | MACKENZIE FINANCIAL CORP | 963,354 | $2.3M | 0.0% | 0.2% | +24.7% |
| 19 | ADAR1 Capital Management, LLC | 750,000 | $1.8M | 0.1% | 0.2% | 0.0% |
| 20 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 696,776 | $1.7M | 0.0% | 0.2% | -67.2% |
| 21 | ACADIAN ASSET MANAGEMENT LLC | 696,617 | $1.7M | 0.0% | 0.2% | +56.4% |
| 22 | UBS Group AG | 684,713 | $1.6M | 0.0% | 0.2% | -72.4% |
| 23 | TWO SIGMA INVESTMENTS, LP | 643,444 | $1.5M | 0.0% | 0.1% | -46.4% |
| 24 | Nuveen, LLCNEW | 586,664 | $1.4M | 0.0% | 0.1% | new |
| 25 | Bank of New York Mellon Corp | 568,706 | $1.4M | 0.0% | 0.1% | +1971.1% |
Source: SEC Form 13F-HR filings (institutional managers over $100M in US-listed positions). 13Fs disclose long positions only, up to 45 days after quarter end; each manager's latest filed quarter is shown per row and dollar values are the manager's filed marks. Aggregates labeled "2026 filers" count only managers whose latest book is a 2026 quarter. Related: valuation · options positioning · supply chain. Research, not investment advice.