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ARCH Venture Management, LLC

Everything this manager disclosed owning in US-listed stocks — its complete Form 13F portfolio · as of 2026-06-30 · filed with the SEC up to 45 days after quarter end · CIK 0001274403

$1.10B

disclosed book value

12

positions

16%

largest position share

Positions, as of 2026-06-30

top 12 of 12 · 13F covers long US-listed positions only — cash, bonds, private and foreign stakes are not disclosed · PUT/CALL tags = options positions (share-equivalents), not shares held

#IssuerSharesValue% of book
1PBLSPARABILIS MEDICINES INC6.4M$175.5M16%
2BEAMBEAM THERAPEUTICS INC4.5M$155.8M14.2%
3RAPPRAPPORT THERAPEUTICS INC3.7M$155.4M14.1%
4SPTXSEAPORT THERAPEUTICS INC6.3M$136.6M12.4%
5ERASERASCA INC7.1M$129.9M11.8%
6VIRVIR BIOTECHNOLOGY INC12.7M$129.4M11.8%
7MAZEMAZE THERAPEUTICS INC4.1M$123.0M11.2%
8LYELLYELL IMMUNOPHARMA INC3.2M$45.5M4.1%
9GENBGENERATE BIOMEDICINES INC1.9M$32.8M3%
10TXG10X GENOMICS INC217,834$8.4M0.8%
11BOLDBOUNDLESS BIO INC2.7M$6.7M0.6%
12GOSSGOSSAMER BIO INC8.1M$1.3M0.1%

Source: SEC Form 13F-HR, reporting period 2026-06-30. Values are the manager's filed June-30-style quarter-end marks, not live prices. Research, not investment advice.

EvidInvest is an independent research and information tool. Figures are calculated from public SEC filings and third-party market data and are provided for informational and educational purposes only. EvidInvest does not provide investment advice, brokerage, or financial services, and is not affiliated with any company it covers. Verify all figures against primary sources before making any decision.