Who owns Orchestra BioMed Holdings, Inc.?
Prices and market caps: Cboe delayed data, at least 15 minutes delayed. Not real-time. Fundamentals from company filings.
Institutional ownership of OBIO from SEC Form 13F filings across 77 reporting managers. All positions are from one synchronized reporting period — 2026-06-30 books, filed up to 45 days after quarter end — so every row is comparable.
As of the 2026-06-30 reporting period, 77 institutions disclosed 27.7M shares of Orchestra BioMed Holdings, Inc. worth $119.4M — about 43.4% of shares outstanding; the largest disclosed holder is RTW INVESTMENTS, LP. Source: SEC Form 13F filings, parsed by EvidInvest.
77
13F holders
$119.4M
value, 2026 filers
43.4%
of shares outstanding (27.7M sh)
25
new positions (2026 filers)
Top institutional holders
ordered by shares owned · positions as of 2026-06-30 · % of fund = share of the manager's own book · % of co. = share of OBIO's shares outstanding
| # | Manager | Shares | Value | % of fund | % of co. | Δ shares QoQ |
|---|---|---|---|---|---|---|
| 1 | RTW INVESTMENTS, LP | 9.6M | $41.2M | 0.4% | 15% | +15.0% |
| 2 | PERCEPTIVE ADVISORS LLC | 5.0M | $21.7M | 0.3% | 7.9% | 0.0% |
| 3 | BlackRock, Inc. | 2.5M | $10.8M | 0.0% | 3.9% | +294.9% |
| 4 | VANGUARD CAPITAL MANAGEMENT LLC | 2.0M | $8.7M | 0.0% | 3.2% | -8.2% |
| 5 | GEODE CAPITAL MANAGEMENT, LLC | 1.0M | $4.4M | 0.0% | 1.6% | +107.6% |
| 6 | Alyeska Investment Group, L.P. | 1.0M | $4.3M | 0.0% | 1.6% | 0.0% |
| 7 | Propel Bio Management, LLC | 896,701 | $3.9M | 2.0% | 1.4% | 0.0% |
| 8 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLCNEW | 642,154 | $2.8M | 0.0% | 1% | new |
| 9 | STATE STREET CORP | 516,050 | $2.2M | 0.0% | 0.8% | +204.6% |
| 10 | RICE HALL JAMES & ASSOCIATES, LLC | 424,000 | $1.8M | 0.1% | 0.7% | +2131.5% |
| 11 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 349,544 | $1.5M | 0.0% | 0.5% | +31.7% |
| 12 | NORTHERN TRUST CORP | 343,640 | $1.5M | 0.0% | 0.5% | +190.5% |
| 13 | UBS Group AG | 325,773 | $1.4M | 0.0% | 0.5% | +547.5% |
| 14 | VANGUARD FIDUCIARY TRUST CO | 292,253 | $1.3M | 0.0% | 0.5% | +24.2% |
| 15 | VANGUARD PORTFOLIO MANAGEMENT LLCNEW | 274,973 | $1.2M | 0.0% | 0.4% | new |
| 16 | Knott David M Jr | 253,651 | $1.1M | 0.6% | 0.4% | 0.0% |
| 17 | Flat Footed LLCNEW | 251,372 | $1.1M | 0.1% | 0.4% | new |
| 18 | Simplify Asset Management Inc. | 219,387 | $946,655 | 0.0% | 0.3% | 0.0% |
| 19 | GOLDMAN SACHS GROUP INC | 179,606 | $775,000 | 0.0% | 0.3% | +15.7% |
| 20 | DAFNA Capital Management LLC | 126,841 | $547,319 | 0.1% | 0.2% | 0.0% |
| 21 | Daytona Street Capital LLC | 96,398 | $379,336 | 0.3% | 0.2% | +83.3% |
| 22 | RENAISSANCE TECHNOLOGIES LLC | 90,000 | $388,350 | 0.0% | 0.1% | +26.9% |
| 23 | IFP Advisors, Inc | 89,608 | $386,659 | 0.0% | 0.1% | -9.4% |
| 24 | Bank of New York Mellon CorpNEW | 86,103 | $371,534 | 0.0% | 0.1% | new |
| 25 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 80,600 | $347,789 | 0.0% | 0.1% | +14.2% |
Source: SEC Form 13F-HR filings (institutional managers over $100M in US-listed positions). 13Fs disclose long positions only, up to 45 days after quarter end; each manager's latest filed quarter is shown per row and dollar values are the manager's filed marks. Aggregates labeled "2026 filers" count only managers whose latest book is a 2026 quarter. Related: valuation · options positioning · supply chain. Research, not investment advice.