Holders — by stockHoldings — by fund
PERCEPTIVE ADVISORS LLC
Everything this manager disclosed owning in US-listed stocks — its complete Form 13F portfolio · as of 2026-06-30 · filed with the SEC up to 45 days after quarter end · CIK 0001224962
$6.66B
disclosed book value
108
positions
10.2%
largest position share
Positions, as of 2026-06-30
top 100 of 108 · 13F covers long US-listed positions only — cash, bonds, private and foreign stakes are not disclosed · PUT/CALL tags = options positions (share-equivalents), not shares held
| # | Issuer | Shares | Value | % of book |
|---|---|---|---|---|
| 1 | PRAXPRAXIS PRECISION MEDICINES I | 2.0M | $681.6M | 10.2% |
| 2 | SYRESPYRE THERAPEUTICS INC | 4.3M | $383.5M | 5.8% |
| 3 | CELCCELCUITY INC | 3.2M | $334.5M | 5% |
| 4 | ASNDASCENDIS PHARMA A/S | 1.2M | $310.4M | 4.7% |
| 5 | RYTMRHYTHM PHARMACEUTICALS INC | 2.6M | $287.2M | 4.3% |
| 6 | ROIVROIVANT SCIENCES LTD | 8.1M | $286.1M | 4.3% |
| 7 | RLAYRELAY THERAPEUTICS INC | 14.1M | $263.9M | 4% |
| 8 | TVTXTRAVERE THERAPEUTICS INC | 3.8M | $213.2M | 3.2% |
| 9 | KARDKARDIGAN INC | 8.2M | $195.6M | 2.9% |
| 10 | NUVALENT INC | 1.6M | $195.2M | 2.9% |
| 11 | EWTXEDGEWISE THERAPEUTICS INC | 4.4M | $177.7M | 2.7% |
| 12 | APGEAPOGEE THERAPEUTICS INC | 1.3M | $173.6M | 2.6% |
| 13 | AMLXAMYLYX PHARMACEUTICALS INC | 8.3M | $149.7M | 2.2% |
| 14 | MGTXMEIRAGTX HLDGS PLC | 10.8M | $145.7M | 2.2% |
| 15 | ORKAORUKA THERAPEUTICS INC | 1.3M | $128.0M | 1.9% |
| 16 | INBXINHIBRX BIOSCIENCES INC | 1.3M | $123.0M | 1.8% |
| 17 | PTGXPROTAGONIST THERAPEUTICS INC | 981,879 | $120.4M | 1.8% |
| 18 | SLDBSOLID BIOSCIENCES INC | 11.9M | $118.9M | 1.8% |
| 19 | ZYMEZYMEWORKS INC | 4.2M | $109.3M | 1.6% |
| 20 | TNGXTANGO THERAPEUTICS INC | 3.4M | $105.6M | 1.6% |
| 21 | IMTXIMMATICS N.V | 10.4M | $105.2M | 1.6% |
| 22 | NRIXNURIX THERAPEUTICS INC | 4.3M | $104.8M | 1.6% |
| 23 | BCRXBIOCRYST PHARMACEUTICALS INC | 10.3M | $103.1M | 1.5% |
| 24 | RVMDREVOLUTION MEDICINES INC | 527,600 | $98.8M | 1.5% |
| 25 | AVLNAVALYN PHARMACEUTICALS INC | 2.7M | $88.1M | 1.3% |
| 26 | MRNAMODERNA INCPUT | 1.0M | $70.0M | 1.1% |
| 27 | DYNDYNE THERAPEUTICS INC | 2.7M | $59.7M | 0.9% |
| 28 | BIIBBIOGEN INC | 276,173 | $59.7M | 0.9% |
| 29 | IMVTIMMUNOVANT INC | 1.4M | $52.3M | 0.8% |
| 30 | UNHUNITEDHEALTH GROUP INC | 116,806 | $48.5M | 0.7% |
| 31 | XBISPDR SERIES TRUSTPUT | 300,000 | $47.5M | 0.7% |
| 32 | IONSIONIS PHARMACEUTICALS INC | 566,000 | $44.9M | 0.7% |
| 33 | STROSUTRO BIOPHARMA INC | 1.3M | $43.3M | 0.7% |
| 34 | ANROALTO NEUROSCIENCE INC | 1.6M | $42.5M | 0.6% |
| 35 | JAZZJAZZ PHARMACEUTICALS PLC | 170,000 | $41.0M | 0.6% |
| 36 | CRVSCORVUS PHARMACEUTICALS INC | 2.7M | $39.9M | 0.6% |
| 37 | SIONSIONNA THERAPEUTICS INC | 905,000 | $39.8M | 0.6% |
| 38 | CTMXCYTOMX THERAPEUTICS INC. | 10.4M | $39.1M | 0.6% |
| 39 | AORTARTIVION INC | 1.7M | $39.0M | 0.6% |
| 40 | XFORX4 PHARMACEUTICALS INC | 7.9M | $37.0M | 0.6% |
| 41 | CORTCORCEPT THERAPEUTICS INC | 398,385 | $34.6M | 0.5% |
| 42 | RGENREPLIGEN CORP | 248,212 | $33.9M | 0.5% |
| 43 | AVRANTERIS TECHNOLOGIES GLOBAL | 3.4M | $33.7M | 0.5% |
| 44 | RAPPRAPPORT THERAPEUTICS INC | 773,342 | $32.2M | 0.5% |
| 45 | DMRADAMORA THERAPEUTICS INC | 1.2M | $31.8M | 0.5% |
| 46 | CRLCHARLES RIV LABS INTL INC | 140,000 | $31.8M | 0.5% |
| 47 | AXSMAXSOME THERAPEUTICS INC. | 118,450 | $29.0M | 0.4% |
| 48 | EYPTEYEPOINT INCPUT | 2.0M | $28.6M | 0.4% |
| 49 | DBVTDBV TECHNOLOGIES S A | 1.7M | $27.1M | 0.4% |
| 50 | IRTCIRHYTHM HOLDINGS INC | 223,766 | $26.6M | 0.4% |
| 51 | ADPTADAPTIVE BIOTECHNOLOGIES COR | 1.2M | $26.1M | 0.4% |
| 52 | SABSSAB BIOTHERAPEUTICS INC | 6.6M | $25.8M | 0.4% |
| 53 | DHRDANAHER CORP DEL | 130,000 | $24.8M | 0.4% |
| 54 | TENXTENAX THERAPEUTICS INC | 1.7M | $24.7M | 0.4% |
| 55 | CAPRCAPRICOR THERAPEUTICS INCCALL | 1.0M | $24.1M | 0.4% |
| 56 | SLSSELLAS LIFE SCIENCES GROUP IPUT | 1.5M | $22.1M | 0.3% |
| 57 | NAUTNAUTILUS BIOTECHNOLOGY INC | 11.6M | $21.8M | 0.3% |
| 58 | OBIOORCHESTRA BIOMED HLDGS INC | 5.0M | $21.7M | 0.3% |
| 59 | ISRGINTUITIVE SURGICAL INC | 51,884 | $20.6M | 0.3% |
| 60 | ANLADLAI NORTYE LTD | 1.8M | $20.6M | 0.3% |
| 61 | CTNMCONTINEUM THERAPEUTICS INC | 1.3M | $20.6M | 0.3% |
| 62 | NVCTNUVECTIS PHARMA INC | 1.0M | $18.4M | 0.3% |
| 63 | PALIPALISADE BIO INC | 8.4M | $17.6M | 0.3% |
| 64 | OMDAOMADA HEALTH INC | 786,330 | $17.3M | 0.3% |
| 65 | LONALEONABIO INC | 1.9M | $17.1M | 0.3% |
| 66 | EOLSEVOLUS INC | 2.5M | $17.1M | 0.3% |
| 67 | NAMSNEWAMSTERDAM PHARMA COMPANYPUT | 500,000 | $16.9M | 0.3% |
| 68 | IVVDINVIVYD INC | 18.5M | $16.1M | 0.2% |
| 69 | CELC 2.75 08/01/31CELCUITY INC | 6.5M | $14.6M | 0.2% |
| 70 | MIRMMIRUM PHARMACEUTICALS INC | 115,391 | $13.5M | 0.2% |
| 71 | SRZNSURROZEN INC | 503,985 | $13.1M | 0.2% |
| 72 | BBNXBETA BIONICS INC | 832,944 | $13.1M | 0.2% |
| 73 | CAPRCAPRICOR THERAPEUTICS INCPUT | 500,000 | $12.0M | 0.2% |
| 74 | AXGNAXOGEN INC | 247,312 | $11.4M | 0.2% |
| 75 | OSCROSCAR HEALTH INC | 400,000 | $11.4M | 0.2% |
| 76 | OCSOCULIS HOLDING AG | 808,827 | $11.2M | 0.2% |
| 77 | SPTXSEAPORT THERAPEUTICS INC | 500,000 | $10.9M | 0.2% |
| 78 | VRDNVIRIDIAN THERAPEUTICS INC | 581,980 | $10.7M | 0.2% |
| 79 | BSXBOSTON SCIENTIFIC CORP | 250,000 | $10.7M | 0.2% |
| 80 | BLLNBILLIONTOONE INC | 86,812 | $10.4M | 0.2% |
| 81 | ABVXABIVAX SA | 74,000 | $9.9M | 0.1% |
| 82 | NTRANATERA INC | 34,689 | $9.4M | 0.1% |
| 83 | ENGNENGENE THERAPEUTICS INC | 4.8M | $8.3M | 0.1% |
| 84 | RACCRESEARCH ALLIANCE CORP III | 750,000 | $8.0M | 0.1% |
| 85 | AGMBAGOMAB THERAPEUTICS NV | 600,000 | $7.8M | 0.1% |
| 86 | CGEMCULLINAN THERAPEUTICS INC | 426,478 | $7.8M | 0.1% |
| 87 | QUREUNIQURE NV | 168,000 | $7.7M | 0.1% |
| 88 | MOBIMOBIA MED INC | 523,654 | $7.0M | 0.1% |
| 89 | ADGMADAGIO MED HLDGS INC | 9.9M | $6.4M | 0.1% |
| 90 | GHGUARDANT HEALTH INC | 41,327 | $6.2M | 0.1% |
| 91 | PHATPHATHOM PHARMACEUTICALS INC | 532,000 | $5.8M | 0.1% |
| 92 | OTLKOUTLOOK THERAPEUTICS INC | 3.1M | $5.0M | 0.1% |
| 93 | COGTCOGENT BIOSCIENCES INC | 121,082 | $4.7M | 0.1% |
| 94 | EDSAEDESA BIOTECH INC | 563,239 | $4.6M | 0.1% |
| 95 | AVTXAVALO THERAPEUTICS INC | 219,813 | $4.1M | 0.1% |
| 96 | TWSTTWIST BIOSCIENCE CORP | 36,812 | $3.8M | 0.1% |
| 97 | CBIOCRESCENT BIOPHARMA INC. | 206,942 | $3.7M | 0.1% |
| 98 | XERSXERIS BIOPHARMA HOLDINGS INC | 467,013 | $3.7M | 0.1% |
| 99 | OMOUTSET MED INC | 833,333 | $3.6M | 0.1% |
| 100 | BDSXBIODESIX INC | 108,694 | $2.5M | 0% |
Source: SEC Form 13F-HR, reporting period 2026-06-30. Values are the manager's filed June-30-style quarter-end marks, not live prices. Research, not investment advice.