Who owns Septerna Inc?
Institutional ownership of SEPN from SEC Form 13F filings across 112 reporting managers. All positions are from one synchronized reporting period — 2026-06-30 books, filed up to 45 days after quarter end — so every row is comparable.
112
13F holders
$462.0M
value, 2026 filers
30.8%
of shares outstanding (13.9M sh)
37
new positions (2026 filers)
Top institutional holders
ordered by shares owned · positions as of 2026-06-30· % of fund = share of the manager's own book · % of co. = share of SEPN's shares outstanding
| # | Manager | Shares | Value | % of fund | % of co. | Δ shares QoQ |
|---|---|---|---|---|---|---|
| 1 | GOLDMAN SACHS GROUP INC | 3.1M | $102.6M | 0.0% | 6.8% | +5.4% |
| 2 | BlackRock, Inc. | 1.9M | $64.7M | 0.0% | 4.3% | +6.0% |
| 3 | Jupiter Topco LLCNEW | 1.3M | $43.7M | 0.0% | 2.9% | new |
| 4 | VANGUARD CAPITAL MANAGEMENT LLC | 1.2M | $40.9M | 0.0% | 2.7% | -49.0% |
| 5 | PRIMECAP MANAGEMENT CO/CA/ | 1.2M | $39.1M | 0.0% | 2.6% | +11.3% |
| 6 | GEODE CAPITAL MANAGEMENT, LLC | 679,163 | $22.8M | 0.0% | 1.5% | +5.3% |
| 7 | Catalio Capital Management, LP | 536,152 | $18.0M | 3.4% | 1.2% | +82.1% |
| 8 | Balyasny Asset Management L.P. | 350,442 | $11.7M | 0.0% | 0.8% | +48.1% |
| 9 | Longaeva Partners L.P. | 298,171 | $10.0M | 0.2% | 0.7% | +299.9% |
| 10 | VANGUARD PORTFOLIO MANAGEMENT LLC | 230,184 | $7.7M | 0.0% | 0.5% | +18.0% |
| 11 | Universal- Beteiligungs- und Servicegesellschaft mbH | 222,702 | $7.5M | 0.0% | 0.5% | -0.6% |
| 12 | TWO SIGMA INVESTMENTS, LP | 220,885 | $7.4M | 0.0% | 0.5% | +193.1% |
| 13 | NORTHERN TRUST CORP | 201,131 | $6.7M | 0.0% | 0.4% | +22.2% |
| 14 | Sixth Street Partners Management Company, L.P.NEW | 187,041 | $6.3M | 1.1% | 0.4% | new |
| 15 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 187,041 | $6.3M | 0.0% | 0.4% | +3.0% |
| 16 | Woodline Partners LPNEW | 185,535 | $6.2M | 0.0% | 0.4% | new |
| 17 | VANGUARD FIDUCIARY TRUST CO | 165,656 | $5.5M | 0.0% | 0.4% | +7.2% |
| 18 | MORGAN STANLEY | 134,377 | $4.5M | 0.0% | 0.3% | +21.6% |
| 19 | UBS Group AG | 89,874 | $3.0M | 0.0% | 0.2% | -23.2% |
| 20 | FEDERATED HERMES, INC. | 86,753 | $2.9M | 0.0% | 0.2% | -2.9% |
| 21 | JPMORGAN CHASE & CO | 85,301 | $3.0M | 0.0% | 0.2% | +0.7% |
| 22 | LAZARD ASSET MANAGEMENT LLCNEW | 75,425 | $2.5M | 0.0% | 0.2% | new |
| 23 | ARROWSTREET CAPITAL, LIMITED PARTNERSHIPNEW | 74,649 | $2.5M | 0.0% | 0.2% | new |
| 24 | AMERICAN CENTURY COMPANIES INC | 60,973 | $2.0M | 0.0% | 0.1% | -0.5% |
| 25 | Bank of New York Mellon Corp | 56,176 | $1.9M | 0.0% | 0.1% | -4.3% |
Source: SEC Form 13F-HR filings (institutional managers over $100M in US-listed positions). 13Fs disclose long positions only, up to 45 days after quarter end; each manager's latest filed quarter is shown per row and dollar values are the manager's filed marks. Aggregates labeled "2026 filers" count only managers whose latest book is a 2026 quarter. Related: valuation · options positioning · supply chain. Research, not investment advice.