Who owns Prelude Therapeutics Inc?
Prices and market caps: Cboe delayed data, at least 15 minutes delayed. Not real-time. Fundamentals from company filings.
Institutional ownership of PRLD from SEC Form 13F filings across 75 reporting managers. All positions are from one synchronized reporting period — 2026-06-30 books, filed up to 45 days after quarter end — so every row is comparable.
As of the 2026-06-30 reporting period, 75 institutions disclosed 49.6M shares of Prelude Therapeutics Inc worth $264.3M — about 50.4% of shares outstanding; the largest disclosed holder is ORBIMED ADVISORS LLC. Source: SEC Form 13F filings, parsed by EvidInvest.
75
13F holders
$264.3M
value, 2026 filers
50.4%
of shares outstanding (49.6M sh)
34
new positions (2026 filers)
Top institutional holders
ordered by shares owned · positions as of 2026-06-30 · % of fund = share of the manager's own book · % of co. = share of PRLD's shares outstanding
| # | Manager | Shares | Value | % of fund | % of co. | Δ shares QoQ |
|---|---|---|---|---|---|---|
| 1 | ORBIMED ADVISORS LLC | 13.7M | $73.2M | 1.4% | 13.9% | +25.8% |
| 2 | BAKER BROS. ADVISORS LP | 10.1M | $54.0M | 0.3% | 10.3% | 0.0% |
| 3 | RA CAPITAL MANAGEMENT, L.P.NEW | 6.5M | $34.5M | 0.3% | 6.6% | new |
| 4 | Soleus Capital Management, L.P.NEW | 3.4M | $18.0M | 0.6% | 3.4% | new |
| 5 | Kynam Capital Management, LP | 2.4M | $12.9M | 0.7% | 2.5% | +51.6% |
| 6 | VANGUARD CAPITAL MANAGEMENT LLC | 2.0M | $10.7M | 0.0% | 2% | +63.3% |
| 7 | BlackRock, Inc. | 1.8M | $9.6M | 0.0% | 1.8% | +458.4% |
| 8 | SPHERA FUNDS MANAGEMENT LTD. | 1.0M | $5.4M | 0.7% | 1% | +82.7% |
| 9 | TWO SIGMA INVESTMENTS, LP | 993,369 | $5.3M | 0.0% | 1% | +7.6% |
| 10 | ADAR1 Capital Management, LLC | 900,900 | $4.8M | 0.2% | 0.9% | +489.5% |
| 11 | MILLENNIUM MANAGEMENT LLC | 844,993 | $4.5M | 0.0% | 0.9% | +120.8% |
| 12 | GEODE CAPITAL MANAGEMENT, LLC | 841,862 | $4.5M | 0.0% | 0.9% | +178.3% |
| 13 | ADAGE CAPITAL PARTNERS GP, L.L.C.NEW | 766,095 | $4.1M | 0.0% | 0.8% | new |
| 14 | ACADIAN ASSET MANAGEMENT LLC | 611,359 | $3.3M | 0.0% | 0.6% | +19.5% |
| 15 | MORGAN STANLEY | 503,860 | $2.7M | 0.0% | 0.5% | +56.4% |
| 16 | STATE STREET CORP | 428,787 | $2.3M | 0.0% | 0.4% | +210.2% |
| 17 | UBS Group AG | 318,797 | $1.7M | 0.0% | 0.3% | +394.2% |
| 18 | VANGUARD FIDUCIARY TRUST CO | 284,886 | $1.5M | 0.0% | 0.3% | +81.0% |
| 19 | RENAISSANCE TECHNOLOGIES LLC | 281,200 | $1.5M | 0.0% | 0.3% | +2.2% |
| 20 | NORTHERN TRUST CORP | 240,599 | $1.3M | 0.0% | 0.2% | +380.0% |
| 21 | VANGUARD PORTFOLIO MANAGEMENT LLCNEW | 193,920 | $1.0M | 0.0% | 0.2% | new |
| 22 | MARSHALL WACE, LLP | 190,692 | $1.0M | 0.0% | 0.2% | -46.9% |
| 23 | Connor, Clark & Lunn Investment Management Ltd. | 125,606 | $669,480 | 0.0% | 0.1% | +15.1% |
| 24 | GOLDMAN SACHS GROUP INC | 120,834 | $644,045 | 0.0% | 0.1% | -48.9% |
| 25 | Hillsdale Investment Management Inc.NEW | 81,400 | $433,862 | 0.0% | 0.1% | new |
Source: SEC Form 13F-HR filings (institutional managers over $100M in US-listed positions). 13Fs disclose long positions only, up to 45 days after quarter end; each manager's latest filed quarter is shown per row and dollar values are the manager's filed marks. Aggregates labeled "2026 filers" count only managers whose latest book is a 2026 quarter. Related: valuation · options positioning · supply chain. Research, not investment advice.