Who owns Prelude Therapeutics Inc?
Prices and market caps: Cboe delayed data, at least 15 minutes delayed. Not real-time. Fundamentals from SEC filings.
Institutional ownership of PRLD from SEC Form 13F filings across 57 reporting managers. All positions are from one synchronized reporting period — 2026-06-30 books, filed up to 45 days after quarter end — so every row is comparable.
As of the 2026-06-30 reporting period, 57 institutions disclosed 24.3M shares of Prelude Therapeutics Inc worth $126.2M — about 24.7% of shares outstanding; the largest disclosed holder is ORBIMED ADVISORS LLC. Source: SEC Form 13F filings, parsed by EvidInvest.
57
13F holders
$126.2M
value, 2026 filers
24.7%
of shares outstanding (24.3M sh)
27
new positions (2026 filers)
Top institutional holders
ordered by shares owned · positions as of 2026-06-30· % of fund = share of the manager's own book · % of co. = share of PRLD's shares outstanding
| # | Manager | Shares | Value | % of fund | % of co. | Δ shares QoQ |
|---|---|---|---|---|---|---|
| 1 | ORBIMED ADVISORS LLC | 13.7M | $73.2M | 1.4% | 13.9% | +25.8% |
| 2 | VANGUARD CAPITAL MANAGEMENT LLC | 2.0M | $10.7M | 0.0% | 2% | -18.3% |
| 3 | BlackRock, Inc. | 1.8M | $9.6M | 0.0% | 1.8% | +458.4% |
| 4 | TWO SIGMA INVESTMENTS, LP | 993,369 | $5.3M | 0.0% | 1% | +7.6% |
| 5 | MILLENNIUM MANAGEMENT LLC | 844,993 | $4.5M | 0.0% | 0.9% | +120.8% |
| 6 | GEODE CAPITAL MANAGEMENT, LLC | 841,862 | $4.5M | 0.0% | 0.9% | +178.3% |
| 7 | ADAGE CAPITAL PARTNERS GP, L.L.C.NEW | 766,095 | $4.1M | 0.0% | 0.8% | new |
| 8 | ACADIAN ASSET MANAGEMENT LLC | 611,359 | $3,253 | 0.0% | 0.6% | +19.5% |
| 9 | MORGAN STANLEY | 503,860 | $2.7M | 0.0% | 0.5% | +56.4% |
| 10 | UBS Group AG | 318,797 | $1.7M | 0.0% | 0.3% | +394.2% |
| 11 | VANGUARD FIDUCIARY TRUST CO | 284,886 | $1.5M | 0.0% | 0.3% | +81.0% |
| 12 | NORTHERN TRUST CORP | 240,599 | $1.3M | 0.0% | 0.2% | +380.0% |
| 13 | VANGUARD PORTFOLIO MANAGEMENT LLCNEW | 193,920 | $1.0M | 0.0% | 0.2% | new |
| 14 | MARSHALL WACE, LLP | 190,692 | $1.0M | 0.0% | 0.2% | -46.9% |
| 15 | Connor, Clark & Lunn Investment Management Ltd. | 125,606 | $669,480 | 0.0% | 0.1% | +15.1% |
| 16 | GOLDMAN SACHS GROUP INC | 120,834 | $644,045 | 0.0% | 0.1% | -48.9% |
| 17 | Bank of New York Mellon CorpNEW | 68,187 | $363,436 | 0.0% | 0.1% | new |
| 18 | Sixth Street Partners Management Company, L.P.NEW | 67,622 | $360,425 | 0.1% | 0.1% | new |
| 19 | CHARLES SCHWAB INVESTMENT MANAGEMENT INCNEW | 67,622 | $360,425 | 0.0% | 0.1% | new |
| 20 | Squarepoint Ops LLCNEW | 59,540 | $317,348 | 0.0% | 0.1% | new |
| 21 | Mariner, LLCNEW | 45,261 | $241,241 | 0.0% | 0% | new |
| 22 | Nuveen, LLCNEW | 37,023 | $197,333 | 0.0% | 0% | new |
| 23 | Invesco Ltd.NEW | 34,742 | $185,175 | 0.0% | 0% | new |
| 24 | Cerity Partners LLC | 32,875 | $175,224 | 0.0% | 0% | 0.0% |
| 25 | DEUTSCHE BANK AG\NEW | 27,824 | $148,302 | 0.0% | 0% | new |
Source: SEC Form 13F-HR filings (institutional managers over $100M in US-listed positions). 13Fs disclose long positions only, up to 45 days after quarter end; each manager's latest filed quarter is shown per row and dollar values are the manager's filed marks. Aggregates labeled "2026 filers" count only managers whose latest book is a 2026 quarter. Related: valuation · options positioning · supply chain. Research, not investment advice.