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Who owns SPRBWhat SPRB owns — n/a

Who owns SPRUCE BIOSCIENCES, INC.?

Prices and market caps: Cboe delayed data, at least 15 minutes delayed. Not real-time. Fundamentals from SEC filings.

Institutional ownership of SPRB from SEC Form 13F filings across 49 reporting managers. All positions are from one synchronized reporting period — 2026-06-30 books, filed up to 45 days after quarter end — so every row is comparable.

As of the 2026-06-30 reporting period, 49 institutions disclosed 1.4M shares of SPRUCE BIOSCIENCES, INC. worth $76.8M — about 58.5% of shares outstanding; the largest disclosed holder is AIGH Capital Management LLC. Source: SEC Form 13F filings, parsed by EvidInvest.

49

13F holders

$76.8M

value, 2026 filers

58.5%

of shares outstanding (1.4M sh)

28

new positions (2026 filers)

Top institutional holders

ordered by shares owned · positions as of 2026-06-30· % of fund = share of the manager's own book · % of co. = share of SPRB's shares outstanding

#ManagerSharesValue% of fund% of co.Δ shares QoQ
1AIGH Capital Management LLCNEW250,000$13.5M0.9%10.3%new
2ORBIMED ADVISORS LLCNEW200,000$10.8M0.2%8.2%new
3BlackRock, Inc.187,836$10.1M0.0%7.7%+1009.0%
4MILLENNIUM MANAGEMENT LLC160,981$8.7M0.0%6.6%+43.9%
5VANGUARD CAPITAL MANAGEMENT LLC119,331$6.4M0.0%4.9%+550.8%
6GEODE CAPITAL MANAGEMENT, LLC70,548$3.8M0.0%2.9%+447.4%
7CITADEL ADVISORS LLC51,905$2.8M0.0%2.1%-25.8%
8BOOTHBAY FUND MANAGEMENT, LLC42,080$2.3M0.0%1.7%0.0%
9Carlyle Group Inc.38,620$2.1M0.0%1.6%0.0%
10GOLDMAN SACHS GROUP INC32,348$1.7M0.0%1.3%+487.5%
11DIADEMA PARTNERS LP30,000$1.6M0.2%1.2%+200.0%
12Point72 Asset Management, L.P.NEW28,278$1.5M0.0%1.2%new
13UBS Group AG23,381$1.3M0.0%1%+496.6%
14ExodusPoint Capital Management, LP22,000$1.2M0.0%0.9%0.0%
15NORTHERN TRUST CORPNEW21,083$1.1M0.0%0.9%new
16Knott David M JrNEW20,000$1.1M0.6%0.8%new
17AMERIPRISE FINANCIAL INCNEW18,834$1.0M0.0%0.8%new
18VANGUARD PORTFOLIO MANAGEMENT LLCNEW18,496$998,7840.0%0.8%new
19VANGUARD FIDUCIARY TRUST CO18,361$991,4940.0%0.8%+233.0%
20Balyasny Asset Management L.P.12,138$655,4520.0%0.5%-69.7%
21Persistent Asset Partners Ltd7,677$414,5580.1%0.3%+203.7%
22STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEMNEW7,182$387,8280.0%0.3%new
23Bank of New York Mellon CorpNEW6,779$366,0570.0%0.3%new
24Sixth Street Partners Management Company, L.P.NEW5,896$318,3840.1%0.2%new
25CHARLES SCHWAB INVESTMENT MANAGEMENT INCNEW5,896$318,3840.0%0.2%new

Source: SEC Form 13F-HR filings (institutional managers over $100M in US-listed positions). 13Fs disclose long positions only, up to 45 days after quarter end; each manager's latest filed quarter is shown per row and dollar values are the manager's filed marks. Aggregates labeled "2026 filers" count only managers whose latest book is a 2026 quarter. Related: valuation · options positioning · supply chain. Research, not investment advice.

EvidInvest is an independent research and information tool. Figures are calculated from public SEC filings and third-party market data and are provided for informational and educational purposes only. EvidInvest does not provide investment advice, brokerage, or financial services, and is not affiliated with any company it covers. Verify all figures against primary sources before making any decision.