Who owns Tyra Biosciences, Inc.?
Prices and market caps: Cboe delayed data, at least 15 minutes delayed. Not real-time. Fundamentals from company filings.
Institutional ownership of TYRA from SEC Form 13F filings across 168 reporting managers. All positions are from one synchronized reporting period — 2026-06-30 books, filed up to 45 days after quarter end — so every row is comparable.
As of the 2026-06-30 reporting period, 168 institutions disclosed 69.3M shares of Tyra Biosciences, Inc. worth $2.22B — about 105.1% of shares outstanding; the largest disclosed holder is RA CAPITAL MANAGEMENT, L.P.. Source: SEC Form 13F filings, parsed by EvidInvest.
168
13F holders
$2.22B
value, 2026 filers
105.1%
of shares outstanding (69.3M sh)
32
new positions (2026 filers)
Top institutional holders
ordered by shares owned · positions as of 2026-06-30 · % of fund = share of the manager's own book · % of co. = share of TYRA's shares outstanding
| # | Manager | Shares | Value | % of fund | % of co. | Δ shares QoQ |
|---|---|---|---|---|---|---|
| 1 | RA CAPITAL MANAGEMENT, L.P. | 12.2M | $389.6M | 3.4% | 18.5% | 0.0% |
| 2 | FMR LLC | 8.9M | $284.9M | 0.0% | 13.5% | +15.1% |
| 3 | Jupiter Topco LLCNEW | 4.4M | $139.2M | 0.1% | 6.6% | new |
| 4 | Alta Partners Management Company, L.P. | 3.8M | $122.1M | 95.9% | 5.8% | 0.0% |
| 5 | Nextech Invest Ltd. | 3.6M | $113.5M | 5.4% | 5.4% | -12.4% |
| 6 | TCG Crossover Management, LLC | 3.2M | $103.8M | 2.5% | 4.9% | 0.0% |
| 7 | BlackRock, Inc. | 3.0M | $96.8M | 0.0% | 4.6% | +36.7% |
| 8 | PRICE T ROWE ASSOCIATES INC /MD/ | 2.8M | $88.9M | 0.0% | 4.2% | +182.2% |
| 9 | STATE STREET CORP | 2.1M | $68.4M | 0.0% | 3.2% | +76.0% |
| 10 | Commodore Capital LP | 1.9M | $59.9M | 3.6% | 2.8% | -24.2% |
| 11 | Paradigm Biocapital Advisors LP | 1.8M | $58.4M | 1.1% | 2.8% | -11.0% |
| 12 | VANGUARD CAPITAL MANAGEMENT LLC | 1.5M | $48.2M | 0.0% | 2.3% | +34.0% |
| 13 | BVF INC/IL | 1.5M | $47.1M | 1.2% | 2.2% | -25.3% |
| 14 | 5AM Venture Management, LLC | 1.0M | $32.9M | 11.4% | 1.6% | 0.0% |
| 15 | DEERFIELD MANAGEMENT COMPANY, L.P. | 1.0M | $32.5M | 0.3% | 1.5% | +85.2% |
| 16 | Hood River Capital Management LLCNEW | 1.0M | $32.5M | 0.2% | 1.5% | new |
| 17 | GEODE CAPITAL MANAGEMENT, LLC | 970,734 | $31.0M | 0.0% | 1.5% | +47.4% |
| 18 | Caligan Partners LP | 806,986 | $25.8M | 1.2% | 1.2% | -36.8% |
| 19 | Canaan Partners XI LLC | 750,000 | $24.0M | 18.8% | 1.1% | 0.0% |
| 20 | Siren, L.L.C.NEW | 725,000 | $23.2M | 0.5% | 1.1% | new |
| 21 | Sio Capital Management, LLC | 695,315 | $22.2M | 3.7% | 1.1% | +14.8% |
| 22 | STEMPOINT CAPITAL LP | 632,754 | $20.2M | 3.5% | 1% | +227.6% |
| 23 | MARSHALL WACE, LLP | 583,133 | $18.6M | 0.0% | 0.9% | +194.9% |
| 24 | GOLDMAN SACHS GROUP INC | 463,477 | $14.8M | 0.0% | 0.7% | -15.8% |
| 25 | JENNISON ASSOCIATES LLC | 450,964 | $14.4M | 0.0% | 0.7% | -28.7% |
Source: SEC Form 13F-HR filings (institutional managers over $100M in US-listed positions). 13Fs disclose long positions only, up to 45 days after quarter end; each manager's latest filed quarter is shown per row and dollar values are the manager's filed marks. Aggregates labeled "2026 filers" count only managers whose latest book is a 2026 quarter. Related: valuation · options positioning · supply chain. Research, not investment advice.