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5AM Venture Management, LLC

Everything this manager disclosed owning in US-listed stocks — its complete Form 13F portfolio · as of 2026-06-30 · filed with the SEC up to 45 days after quarter end · CIK 0001799883

$287.9M

disclosed book value

16

positions

11.8%

largest position share

Positions, as of 2026-06-30

top 16 of 16 · 13F covers long US-listed positions only — cash, bonds, private and foreign stakes are not disclosed · PUT/CALL tags = options positions (share-equivalents), not shares held

#IssuerSharesValue% of book
1MPLTMAPLIGHT THERAPEUTICS INC950,011$34.0M11.8%
2TYRATYRA BIOSCIENCES INC1.0M$32.9M11.4%
3TRDAENTRADA THERAPEUTICS INC4.1M$29.9M10.4%
4PHARVARIS N V797,600$27.6M9.6%
5CAMPCAMP4 THERAPEUTICS CORP5.9M$25.6M8.9%
6ARTVARTIVA BIOTHERAPEUTICS INC2.4M$22.8M7.9%
7TECXTECTONIC THERAPEUTIC INC606,660$20.9M7.2%
8ZNTLZENTALIS PHARMACEUTICALS INC3.9M$19.1M6.7%
9CLDXCELLDEX THERAPEUTICS INC NEW497,270$18.5M6.4%
10EYPTEYEPOINT INC1.1M$15.0M5.2%
11BIOHAVEN LTD738,972$11.0M3.8%
12SRZNSURROZEN INC271,250$7.0M2.4%
13SKYESKYE BIOSCIENCE INC9.7M$6.7M2.3%
14ALXOALX ONCOLOGY HLDGS INC3.1M$6.3M2.2%
15TARAPROTARA THERAPEUTICS INC1.4M$5.2M1.8%
16SLNSILENCE THERAPEUTICS PLC476,200$5.2M1.8%

Source: SEC Form 13F-HR, reporting period 2026-06-30. Values are the manager's filed June-30-style quarter-end marks, not live prices. Research, not investment advice.

EvidInvest is an independent research and information tool. Figures are calculated from public SEC filings and third-party market data and are provided for informational and educational purposes only. EvidInvest does not provide investment advice, brokerage, or financial services, and is not affiliated with any company it covers. Verify all figures against primary sources before making any decision.